Deletion of Nrf2 enhances susceptibility to eosinophilic sinonasal inflammation in a murine model of rhinosinusitis

BACKGROUND: Oxidative stress exacerbates lower airway diseases including asthma and chronic obstructive pulmonary disease (COPD); however, its role in upper airway (sinonasal) chronic inflammatory disorders is less clear. Nuclear erythroid 2 p45-related factor (Nrf2) is an endogenous mechanism that...

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Detaylı Bibliyografya
Yayımlandı:Int Forum Allergy Rhinol
Asıl Yazarlar: London, Nyall R., Tharakan, Anuj, Mendiola, Michelle, Sussan, Thomas E., Chen, Mengfei, Dobzanski, Alex, Lane, Andrew P., Sidhaye, Venkataramana, Biswal, Shyam, Ramanathan, Murugappan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698143/
https://ncbi.nlm.nih.gov/pubmed/30281933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.22222
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