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Characterization of a novel, papain inducible murine model of eosinophilic rhinosinusitis

BACKGROUND: Eosinophilic chronic rhinosinusitis (ECRS) is a disease characterized by eosinophilic inflammatory infiltrate and a local type 2 cytokine milieu. Current animal models fail to recapitulate many of the innate and adaptive immunological hallmarks of the disease, thus hindering the developm...

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Detalhes bibliográficos
Publicado no:Int Forum Allergy Rhinol
Main Authors: Tharakan, Anuj, Dobzanski, Alex, London, Nyall R., Khalil, Syed M., Surya, Nitya, Lane, Andrew P., Ramanathan, Murugappan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880736/
https://ncbi.nlm.nih.gov/pubmed/29341450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.22072
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