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Disruption of Sinonasal Epithelial Nrf2 Enhances Susceptibility to Rhinosinusitis in a Mouse Model

OBJECTIVES/HYPOTHESIS: Oxidative stress has been postulated to play an important role in chronic rhinosinusitis. Nrf2 is a transcription factor that is involved in the regulation of multiple antioxidant genes and its function has been previously shown to be important in sinonasal inflammation. Altho...

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Detalhes bibliográficos
Publicado no:Laryngoscope
Main Authors: Ramanathan, Murugappan, Tharakan, Anuj, Sidhaye, Venkataramana K., Lane, Andrew P., Biswal, Shyam, London, Nyall R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785671/
https://ncbi.nlm.nih.gov/pubmed/32628788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.28884
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