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Bactericidal Antibiotics Promote Reactive Oxygen Species Formation and Inflammation in Human Sinonasal Epithelial Cells

BACKGROUND: Bactericidal antibiotics have been shown to stimulate reactive oxygen species (ROS) formation in mammalian cells through mitochondrial dysfunction. This results in oxidative tissue damage that may have negative consequences for long-term antibiotic use. Antibiotics are widely and heavily...

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Detalhes bibliográficos
Publicado no:Int Forum Allergy Rhinol
Main Authors: Kohanski, Michael A, Tharakan, Anuj, Lane, Andrew P., Ramanathan, Murugappan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752881/
https://ncbi.nlm.nih.gov/pubmed/26624249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.21646
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