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Bactericidal Antibiotics Promote Reactive Oxygen Species Formation and Inflammation in Human Sinonasal Epithelial Cells

BACKGROUND: Bactericidal antibiotics have been shown to stimulate reactive oxygen species (ROS) formation in mammalian cells through mitochondrial dysfunction. This results in oxidative tissue damage that may have negative consequences for long-term antibiotic use. Antibiotics are widely and heavily...

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Publicat a:Int Forum Allergy Rhinol
Autors principals: Kohanski, Michael A, Tharakan, Anuj, Lane, Andrew P., Ramanathan, Murugappan
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752881/
https://ncbi.nlm.nih.gov/pubmed/26624249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.21646
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