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Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function

Asthma development and pathogenesis are influenced by the interactions of airway epithelial cells and innate and adaptive immune cells in response to allergens. Oxidative stress is an important mediator of asthmatic phenotypes in these cell types. Nuclear erythroid 2-related factor 2 (Nrf2) is a red...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Sussan, Thomas E., Gajghate, Sachin, Chatterjee, Samit, Mandke, Pooja, McCormick, Sarah, Sudini, Kuladeep, Kumar, Sarvesh, Breysse, Patrick N., Diette, Gregory B., Sidhaye, Venkataramana K., Biswal, Shyam
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491510/
https://ncbi.nlm.nih.gov/pubmed/25957295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00398.2014
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