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A Phosphosignaling Adaptor Primes the AAA+ Protease ClpXP to Drive Cell Cycle Regulated Proteolysis

The response regulator CpdR couples phosphorylation events in Caulobacter crescentus with the AAA+ protease ClpXP to provide punctuated degradation of crucial substrates involved in cell cycle regulation. CpdR functions like an adaptor to alter substrate choice by ClpXP, however it remains unclear h...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Lau, Joanne, Hernandez-Alicea, Lisa, Vass, Robert H, Chien, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490964/
https://ncbi.nlm.nih.gov/pubmed/26073542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.05.014
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