Overexpression of mutant HSP27 causes axonal neuropathy in mice

BACKGROUND: Mutations in heat shock 27 kDa protein 1 (HSP27 or HSPB1) cause distal hereditary motor neuropathy (dHMN) or Charcot-Marie-Tooth disease type 2 F (CMT2F) according to unknown factors. Mutant HSP27 proteins affect axonal transport by reducing acetylated tubulin. RESULTS: We generated a tr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biomed Sci
Principais autores: Lee, Jinho, Jung, Sung-Chul, Joo, Jaesoon, Choi, Yu-Ri, Moon, Hyo Won, Kwak, Geon, Yeo, Ha Kyung, Lee, Ji-Su, Ahn, Hye-Jee, Jung, Namhee, Hwang, Sunhee, Rheey, Jingeun, Woo, So-Youn, Kim, Ji Yon, Hong, Young Bin, Choi, Byung-Ok
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490621/
https://ncbi.nlm.nih.gov/pubmed/26141737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0154-y
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados