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Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules
Heat shock protein 27 (HSP27, HSPB1) is an anti-apoptotic protein characterized for its tumorigenic and metastatic properties, and now referenced as a major therapeutic target in many types of cancer. The biochemical properties of HSP27 rely on a structural oligomeric and dynamic organization that i...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5288177/ https://ncbi.nlm.nih.gov/pubmed/27449291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10629 |
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