Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules

Heat shock protein 27 (HSP27, HSPB1) is an anti-apoptotic protein characterized for its tumorigenic and metastatic properties, and now referenced as a major therapeutic target in many types of cancer. The biochemical properties of HSP27 rely on a structural oligomeric and dynamic organization that i...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Kim, Jee Hye, Jung, Ye Jin, Choi, Byeol, Lee, Na Lim, Lee, Hae Jun, Kwak, Soo Yeon, Kwon, Youngjoo, Na, Younghwa, Lee, Yun-Sil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288177/
https://ncbi.nlm.nih.gov/pubmed/27449291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10629
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