Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers

Relationships between heat shock protein 27 (HSP27) and cancer aggressiveness, metastasis, drug resistance, and poor patient outcomes in various cancer types including non-small cell lung cancer (NSCLC) were reported, and inhibition of HSP27 expression is suggested to be a possible strategy for canc...

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Vydáno v:Pharmaceutics
Hlavní autoři: Yoo, Hawon, Choi, Seul-Ki, Lee, Jaeok, Park, So Hyeon, Park, You Na, Hwang, Soo-Yeon, Shin, Jae-Ho, Na, Younghwa, Kwon, Youngjoo, Lee, Hwa Jeong, Lee, Yun-Sil
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145107/
https://ncbi.nlm.nih.gov/pubmed/33925114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050630
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