Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage

In polycystic kidney disease (PKD), the rate of cyst formation and disease progression is highly variable. The lack of predictability in disease progression may be due to additional environmental factors or pathophysiological processes called “third hits.” Diabetes is a growing epidemic, and recent...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Sas, Kelli M., Yin, Hong, Fitzgibbon, Wayne R., Baicu, Catalin F., Zile, Michael R., Steele, Stacy L., Amria, May, Saigusa, Takamitsu, Funk, Jason, Bunni, Marlene A., Siegal, Gene P., Siroky, Brian J., Bissler, John J., Bell, P. Darwin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490377/
https://ncbi.nlm.nih.gov/pubmed/25904703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00652.2014
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