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Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage

In polycystic kidney disease (PKD), the rate of cyst formation and disease progression is highly variable. The lack of predictability in disease progression may be due to additional environmental factors or pathophysiological processes called “third hits.” Diabetes is a growing epidemic, and recent...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Sas, Kelli M., Yin, Hong, Fitzgibbon, Wayne R., Baicu, Catalin F., Zile, Michael R., Steele, Stacy L., Amria, May, Saigusa, Takamitsu, Funk, Jason, Bunni, Marlene A., Siegal, Gene P., Siroky, Brian J., Bissler, John J., Bell, P. Darwin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490377/
https://ncbi.nlm.nih.gov/pubmed/25904703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00652.2014
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