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Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease

The mechanism for early hypertension in polycystic kidney disease (PKD) has not been elucidated. One potential pathway that may contribute to the elevation in blood pressure in PKD is the activation of the intrarenal renin-angiotensin-system (RAS). For example, it has been shown that kidney cyst and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Physiol Rep
Hauptverfasser: Saigusa, Takamitsu, Dang, Yujing, Bunni, Marlene A, Amria, May Y, Steele, Stacy L, Fitzgibbon, Wayne R, Bell, P Darwin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463833/
https://ncbi.nlm.nih.gov/pubmed/25999403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12405
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