Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA

Major biological effects of UVB are attributed to cyclobutane pyrimidine dimers (CPDs), the most common photolesions formed on DNA. To investigate the contribution of CPDs to UVB-induced changes of gene expression, a model system was established by transfecting keratinocytes with pseudouridine-modif...

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Udgivet i:PLoS One
Main Authors: Boros, Gábor, Miko, Edit, Muramatsu, Hiromi, Weissman, Drew, Emri, Eszter, van der Horst, Gijsbertus T. J., Szegedi, Andrea, Horkay, Irén, Emri, Gabriella, Karikó, Katalin, Remenyik, Éva
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488231/
https://ncbi.nlm.nih.gov/pubmed/26121660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131141
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