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Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase

Photolyase uses blue light to restore the major ultraviolet (UV)-induced DNA damage, the cyclobutane pyrimidine dimer (CPD), to two normal bases by splitting the cyclobutane ring. Our earlier studies showed that the overall repair is completed in 700 ps through a cyclic electron-transfer radical mec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Zheyun, Tan, Chuang, Guo, Xunmin, Kao, Ya-Ting, Li, Jiang, Wang, Lijuan, Sancar, Aziz, Zhong, Dongping
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169159/
https://ncbi.nlm.nih.gov/pubmed/21804035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110927108
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