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Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase

Photolyase uses blue light to restore the major ultraviolet (UV)-induced DNA damage, the cyclobutane pyrimidine dimer (CPD), to two normal bases by splitting the cyclobutane ring. Our earlier studies showed that the overall repair is completed in 700 ps through a cyclic electron-transfer radical mec...

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Detalhes bibliográficos
Main Authors: Liu, Zheyun, Tan, Chuang, Guo, Xunmin, Kao, Ya-Ting, Li, Jiang, Wang, Lijuan, Sancar, Aziz, Zhong, Dongping
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169159/
https://ncbi.nlm.nih.gov/pubmed/21804035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110927108
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