Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase

Photolyase uses blue light to restore the major ultraviolet (UV)-induced DNA damage, the cyclobutane pyrimidine dimer (CPD), to two normal bases by splitting the cyclobutane ring. Our earlier studies showed that the overall repair is completed in 700 ps through a cyclic electron-transfer radical mec...

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Bibliographic Details
Main Authors: Liu, Zheyun, Tan, Chuang, Guo, Xunmin, Kao, Ya-Ting, Li, Jiang, Wang, Lijuan, Sancar, Aziz, Zhong, Dongping
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169159/
https://ncbi.nlm.nih.gov/pubmed/21804035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110927108
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