Cyclobutane pyrimidine dimers from UVB exposure induce a hypermetabolic state in keratinocytes via mitochondrial oxidative stress

Ultraviolet B radiation (UVB) is an environmental complete carcinogen, which induces and promotes keratinocyte carcinomas, the most common human malignancies. UVB induces the formation of cyclobutane pyrimidine dimers (CPDs). Repairing CPDs through nucleotide excision repair is slow and error-prone...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Hegedűs, Csaba, Juhász, Tamás, Fidrus, Eszter, Janka, Eszter Anna, Juhász, Gábor, Boros, Gábor, Paragh, György, Uray, Karen, Emri, Gabriella, Remenyik, Éva, Bai, Péter
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708942/
https://ncbi.nlm.nih.gov/pubmed/33264701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101808
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