Cyclobutane pyrimidine dimers from UVB exposure induce a hypermetabolic state in keratinocytes via mitochondrial oxidative stress

Ultraviolet B radiation (UVB) is an environmental complete carcinogen, which induces and promotes keratinocyte carcinomas, the most common human malignancies. UVB induces the formation of cyclobutane pyrimidine dimers (CPDs). Repairing CPDs through nucleotide excision repair is slow and error-prone...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Hegedűs, Csaba, Juhász, Tamás, Fidrus, Eszter, Janka, Eszter Anna, Juhász, Gábor, Boros, Gábor, Paragh, György, Uray, Karen, Emri, Gabriella, Remenyik, Éva, Bai, Péter
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708942/
https://ncbi.nlm.nih.gov/pubmed/33264701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101808
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