Anti-HER2 CD4(+) T-helper type 1 response is a novel immune correlate to pathologic response following neoadjuvant therapy in HER2-positive breast cancer

INTRODUCTION: A progressive loss of circulating anti-human epidermal growth factor receptor-2/neu (HER2) CD4(+) T-helper type 1 (Th1) immune responses is observed in HER2(pos)-invasive breast cancer (IBC) patients relative to healthy controls. Pathologic complete response (pCR) following neoadjuvant...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Datta, Jashodeep, Berk, Erik, Xu, Shuwen, Fitzpatrick, Elizabeth, Rosemblit, Cinthia, Lowenfeld, Lea, Goodman, Noah, Lewis, David A, Zhang, Paul J, Fisher, Carla, Roses, Robert E, DeMichele, Angela, Czerniecki, Brian J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488128/
https://ncbi.nlm.nih.gov/pubmed/25997452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0584-1
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