Progressive loss of anti-HER2 CD4(+) T-helper type 1 response in breast tumorigenesis and the potential for immune restoration

Genomic profiling has identified several molecular oncodrivers in breast tumorigenesis. A thorough understanding of endogenous immune responses to these oncodrivers may provide insights into immune interventions for breast cancer (BC). We investigated systemic anti-HER2/neu CD4(+) T-helper type-1 (T...

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Veröffentlicht in:Oncoimmunology
Hauptverfasser: Datta, Jashodeep, Rosemblit, Cinthia, Berk, Erik, Showalter, Lori, Namjoshi, Prachi, Mick, Rosemarie, Lee, Kathreen P, Brod, Andrew M, Yang, Rachel L, Kelz, Rachel R, Fitzpatrick, Elizabeth, Hoyt, Clifford, Feldman, Michael D, Zhang, Paul J, Xu, Shuwen, Koski, Gary K, Czerniecki, Brian J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589053/
https://ncbi.nlm.nih.gov/pubmed/26451293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1022301
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