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CD4(+) T-helper Type 1 Cytokines and Trastuzumab Facilitate CD8(+) T-cell Targeting of HER-2/neu-expressing Cancers
Vaccination strategies incorporating the immunodominant HLA-A2-restricted HER2/neu-derived peptide 369-377 (HER2(369-377)) are increasingly utilized in HER2/neu-expressing cancer patients. The failure of post-vaccination HER2(369-377)-specific CD8(+) T cells to recognize HLA-A2(pos)HER2/neu-expressi...
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| Publicado en: | Cancer Immunol Res |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556111/ https://ncbi.nlm.nih.gov/pubmed/25791067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0208 |
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