Targeting Nrf2 by dihydro-CDDO-trifluoroethyl amide enhances autophagic clearance and viability of β-cells in a setting of oxidative stress

Nrf2 appears to be a critical regulator of diabetes in rodents. However, the underlying mechanisms as well as the clinical relevance of the Nrf2 signaling in human diabetes remain to be fully understood. Herein, we report that islet expression of Nrf2 is upregulated at an earlier stage of diabetes i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Li, Wenjuan, Wu, Weiwei, Song, Haibo, Wang, Fang, Li, Huanjie, Chen, Li, Lai, Yimu, Janicki, Joseph S., Ward, Keith W., Meyer, Colin J., Wang, Xing Li, Tang, Dongqi, Cui, Taixing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486285/
https://ncbi.nlm.nih.gov/pubmed/24815692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.04.046
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados