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Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans

Apicomplexan parasites cause some of the most severe human diseases including malaria (caused by Plasmodium), toxoplasmosis, and cryptosporidiosis. Treatments are limited by lack of effective drugs and development of resistance to available agents. By exploiting novel features of protein kinases in...

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Bibliografische gegevens
Gepubliceerd in:Trends Pharmacol Sci
Hoofdauteurs: Hui, Raymond, El Bakkouri, Majida, Sibley, L. David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485940/
https://ncbi.nlm.nih.gov/pubmed/26002073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.04.011
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