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Allosteric activation of apicomplexan calcium-dependent protein kinases
Calcium-dependent protein kinases (CDPKs) comprise the major group of Ca(2+)-regulated kinases in plants and protists. It has long been assumed that CDPKs are activated, like other Ca(2+)-regulated kinases, by derepression of the kinase domain (KD). However, we found that removal of the autoinhibito...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568647/ https://ncbi.nlm.nih.gov/pubmed/26305940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505914112 |
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