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Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans

Apicomplexan parasites cause some of the most severe human diseases including malaria (caused by Plasmodium), toxoplasmosis, and cryptosporidiosis. Treatments are limited by lack of effective drugs and development of resistance to available agents. By exploiting novel features of protein kinases in...

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Vydáno v:Trends Pharmacol Sci
Hlavní autoři: Hui, Raymond, El Bakkouri, Majida, Sibley, L. David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485940/
https://ncbi.nlm.nih.gov/pubmed/26002073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.04.011
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