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Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans

Apicomplexan parasites cause some of the most severe human diseases including malaria (caused by Plasmodium), toxoplasmosis, and cryptosporidiosis. Treatments are limited by lack of effective drugs and development of resistance to available agents. By exploiting novel features of protein kinases in...

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Bibliografski detalji
Izdano u:Trends Pharmacol Sci
Glavni autori: Hui, Raymond, El Bakkouri, Majida, Sibley, L. David
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485940/
https://ncbi.nlm.nih.gov/pubmed/26002073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.04.011
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