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Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans

Apicomplexan parasites cause some of the most severe human diseases including malaria (caused by Plasmodium), toxoplasmosis, and cryptosporidiosis. Treatments are limited by lack of effective drugs and development of resistance to available agents. By exploiting novel features of protein kinases in...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Hui, Raymond, El Bakkouri, Majida, Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485940/
https://ncbi.nlm.nih.gov/pubmed/26002073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.04.011
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