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Modelling Myc inhibition as a cancer therapy

Myc is a pleiotropic basic helix–loop–helix leucine zipper transcription factor that coordinates expression of the diverse intracellular and extracellular programs that together are necessary for growth and expansion of somatic cells(1). In principle, this makes inhibition of Myc an attractive pharm...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Soucek, Laura, Whitfield, Jonathan, Martins, Carla P., Finch, Andrew J., Murphy, Daniel J., Sodir, Nicole M., Karnezis, Anthony N., Swigart, Lamorna Brown, Nasi, Sergio, Evan, Gerard I.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485609/
https://ncbi.nlm.nih.gov/pubmed/18716624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07260
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