Modelling Myc inhibition as a cancer therapy

Myc is a pleiotropic basic helix–loop–helix leucine zipper transcription factor that coordinates expression of the diverse intracellular and extracellular programs that together are necessary for growth and expansion of somatic cells(1). In principle, this makes inhibition of Myc an attractive pharm...

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Publicado en:Nature
Autores principales: Soucek, Laura, Whitfield, Jonathan, Martins, Carla P., Finch, Andrew J., Murphy, Daniel J., Sodir, Nicole M., Karnezis, Anthony N., Swigart, Lamorna Brown, Nasi, Sergio, Evan, Gerard I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485609/
https://ncbi.nlm.nih.gov/pubmed/18716624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07260
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