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Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice
The principal reason for failure of targeted cancer therapies is the emergence of resistant clones that regenerate the tumor. Therapeutic efficacy therefore depends on not only how effectively a drug inhibits its target, but also the innate or adaptive functional redundancy of that target and its at...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605464/ https://ncbi.nlm.nih.gov/pubmed/23475959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.205542.112 |
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