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Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

The principal reason for failure of targeted cancer therapies is the emergence of resistant clones that regenerate the tumor. Therapeutic efficacy therefore depends on not only how effectively a drug inhibits its target, but also the innate or adaptive functional redundancy of that target and its at...

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Bibliografische gegevens
Hoofdauteurs: Soucek, Laura, Whitfield, Jonathan R., Sodir, Nicole M., Massó-Vallés, Daniel, Serrano, Erika, Karnezis, Anthony N., Swigart, Lamorna Brown, Evan, Gerard I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605464/
https://ncbi.nlm.nih.gov/pubmed/23475959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.205542.112
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