High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

RAS and BRAF mutations impact treatment and prognosis of metastatic colorectal cancer patients (mCRC), but the knowledge is based on trial patients usually not representative for the general cancer population. Patient characteristics, treatment and efficacy according to KRAS, BRAF and MSI status wer...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Sorbye, Halfdan, Dragomir, Anca, Sundström, Magnus, Pfeiffer, Per, Thunberg, Ulf, Bergfors, Monica, Aasebø, Kristine, Eide, Geir Egil, Ponten, Fredrik, Qvortrup, Camilla, Glimelius, Bengt
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484806/
https://ncbi.nlm.nih.gov/pubmed/26121270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131046
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