High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

RAS and BRAF mutations impact treatment and prognosis of metastatic colorectal cancer patients (mCRC), but the knowledge is based on trial patients usually not representative for the general cancer population. Patient characteristics, treatment and efficacy according to KRAS, BRAF and MSI status wer...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sorbye, Halfdan, Dragomir, Anca, Sundström, Magnus, Pfeiffer, Per, Thunberg, Ulf, Bergfors, Monica, Aasebø, Kristine, Eide, Geir Egil, Ponten, Fredrik, Qvortrup, Camilla, Glimelius, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484806/
https://ncbi.nlm.nih.gov/pubmed/26121270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131046
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