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Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
BACKGROUND: Molecular alterations are well studied in colon cancer, however there is still need for an improved understanding of their prognostic impact. This study aims to characterize colon cancer with regard to KRAS, BRAF, and PIK3CA mutations, microsatellite instability (MSI), and average DNA co...
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| 出版年: | BMC Cancer |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364587/ https://ncbi.nlm.nih.gov/pubmed/25884297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1144-x |
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