Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer

BACKGROUND: Molecular alterations are well studied in colon cancer, however there is still need for an improved understanding of their prognostic impact. This study aims to characterize colon cancer with regard to KRAS, BRAF, and PIK3CA mutations, microsatellite instability (MSI), and average DNA co...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:BMC Cancer
मुख्य लेखकों: Birgisson, Helgi, Edlund, Karolina, Wallin, Ulrik, Påhlman, Lars, Kultima, Hanna Göransson, Mayrhofer, Markus, Micke, Patrick, Isaksson, Anders, Botling, Johan, Glimelius, Bengt, Sundström, Magnus
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364587/
https://ncbi.nlm.nih.gov/pubmed/25884297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1144-x
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