KRAS analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

BACKGROUND: Epidermal growth factor receptor inhibitor therapy is now approved for treatment of metastatic colorectal carcinomas (CRC) in patients with tumors lacking KRAS mutations. Several procedures to detect KRAS mutations have been developed. However, the analytical sensitivity and specificity...

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Detaylı Bibliyografya
Asıl Yazarlar: Sundström, Magnus, Edlund, Karolina, Lindell, Monica, Glimelius, Bengt, Birgisson, Helgi, Micke, Patrick, Botling, Johan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002357/
https://ncbi.nlm.nih.gov/pubmed/21122130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-660
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