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Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
BACKGROUND: Molecular alterations are well studied in colon cancer, however there is still need for an improved understanding of their prognostic impact. This study aims to characterize colon cancer with regard to KRAS, BRAF, and PIK3CA mutations, microsatellite instability (MSI), and average DNA co...
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| Veröffentlicht in: | BMC Cancer |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364587/ https://ncbi.nlm.nih.gov/pubmed/25884297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1144-x |
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