Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9

BACKGROUND: Metastatic colorectal cancer (mCRC) is a disease of older age, but there is a relative lack of knowledge about effects of chemotherapy in older patients as they are under-represented in clinical trials. Little data can guide whether the strategy in older mCRC patients should be a sequent...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Winther, Stine Braendegaard, Österlund, Pia, Berglund, Åke, Glimelius, Bengt, Qvortrup, Camilla, Sorbye, Halfdan, Pfeiffer, Per
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Study Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559862/
https://ncbi.nlm.nih.gov/pubmed/28814275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3526-8
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