Association of SLCO1B1 gene polymorphisms with toxicity response of high dose methotrexate chemotherapy in childhood acute lymphoblastic leukemia

Objective: The present study aims to investigate the correlation of polymorphisms of SLCO1B1 gene with the toxicity during therapy with the high-dose methotrexate (MTX) chemotherapy in childhood acute lymphoblastic leukemia. Methods: We analyzed 2 polymorphisms (rs4149081 and rs11045897) in SLCO1B1...

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Publicado en:Int J Clin Exp Med
Autores principales: Li, Jun, Wang, Xiao-Ru, Zhai, Xiao-Wen, Wang, Hong-Sheng, Qian, Xiao-Wen, Miao, Hui, Zhu, Xiao-Hua
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483916/
https://ncbi.nlm.nih.gov/pubmed/26131212
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