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Role of SIRT1 in the Growth and Regulation of Normal Hematopoietic and Leukemia Stem Cells

PURPOSE OF REVIEW: Recent studies have enhanced our understanding the role of the SIRT1 deacetylase in regulation of normal hematopoietic stem cells (HSC) and leukemia stem cells (LSC), and its importance in regulating autophagy and epigenetic reprogramming in response to metabolic alterations. RECE...

詳細記述

保存先:
書誌詳細
出版年:Curr Opin Hematol
主要な著者: Li, Ling, Bhatia, Ravi
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482757/
https://ncbi.nlm.nih.gov/pubmed/26049753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000152
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