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Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia
Cell fate can be controlled through asymmetric division and segregation of protein determinants. But the regulation of this process in the hematopoietic system is poorly understood. Here we show that the dynein binding protein Lis1 (Pafah1b1) is critically required for blood formation and hematopoie...
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| 發表在: | Nat Genet |
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| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267534/ https://ncbi.nlm.nih.gov/pubmed/24487275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2889 |
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