Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia

Cell fate can be controlled through asymmetric division and segregation of protein determinants. But the regulation of this process in the hematopoietic system is poorly understood. Here we show that the dynein binding protein Lis1 (Pafah1b1) is critically required for blood formation and hematopoie...

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Bibliografski detalji
Izdano u:Nat Genet
Glavni autori: Zimdahl, Bryan, Ito, Takahiro, Blevins, Allen, Bajaj, Jeevisha, Konuma, Takaaki, Weeks, Joi, Koechlein, Claire S., Kwon, Hyog Young, Arami, Omead, Rizzieri, David, Broome, H. Elizabeth, Chuah, Charles, Oehler, Vivian G., Sasik, Roman, Hardiman, Gary, Reya, Tannishtha
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267534/
https://ncbi.nlm.nih.gov/pubmed/24487275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2889
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