CD98-mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia

Acute myelogenous leukemia (AML) is an aggressive disease associated with drug resistance and relapse. To improve therapeutic strategies, it is critical to better understand the mechanisms that underlie AML progression. Here we show that the integrin binding glycoprotein CD98 plays a central role in...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Bajaj, Jeevisha, Konuma, Takaaki, Lytle, Nikki K., Kwon, Hyog Young, Ablack, Jailal N., Cantor, Joseph M., Rizzieri, David, Chuah, Charles, Oehler, Vivian G., Broome, Elizabeth H., Ball, Edward D., van der Horst, Edward H., Ginsberg, Mark H., Reya, Tannishtha
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137811/
https://ncbi.nlm.nih.gov/pubmed/27908736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.10.003
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