CD98-mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia

Acute myelogenous leukemia (AML) is an aggressive disease associated with drug resistance and relapse. To improve therapeutic strategies, it is critical to better understand the mechanisms that underlie AML progression. Here we show that the integrin binding glycoprotein CD98 plays a central role in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Cell
Prif Awduron: Bajaj, Jeevisha, Konuma, Takaaki, Lytle, Nikki K., Kwon, Hyog Young, Ablack, Jailal N., Cantor, Joseph M., Rizzieri, David, Chuah, Charles, Oehler, Vivian G., Broome, Elizabeth H., Ball, Edward D., van der Horst, Edward H., Ginsberg, Mark H., Reya, Tannishtha
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137811/
https://ncbi.nlm.nih.gov/pubmed/27908736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.10.003
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