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Role of SIRT1 in the Growth and Regulation of Normal Hematopoietic and Leukemia Stem Cells
PURPOSE OF REVIEW: Recent studies have enhanced our understanding the role of the SIRT1 deacetylase in regulation of normal hematopoietic stem cells (HSC) and leukemia stem cells (LSC), and its importance in regulating autophagy and epigenetic reprogramming in response to metabolic alterations. RECE...
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| Опубликовано в: : | Curr Opin Hematol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4482757/ https://ncbi.nlm.nih.gov/pubmed/26049753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000152 |
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