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Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation
BACKGROUND: The transcription factor GATA-2 is predominantly expressed in hematopoietic stem and progenitor cells and counteracts the erythroid-specific transcription factor GATA-1, to modulate the proliferation and differentiation of hematopoietic cells. During hematopoietic cell differentiation, G...
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| Pubblicato in: | Drug Des Devel Ther |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4482369/ https://ncbi.nlm.nih.gov/pubmed/26124638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S81911 |
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