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Requirement of the Histone Demethylase LSD1 in Snai1-mediated Transcriptional Repression during Epithelial-Mesenchymal Transition

Epithelial-mesenchymal transition (EMT) plays pivotal roles during embryonic development and carcinoma progression. Members of the Snail family of zinc finger transcription factors are central mediators of EMT and induce EMT in part by directly repressing epithelial markers such as E-cadherin, a gat...

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Detalhes bibliográficos
Main Authors: Lin, Tong, Ponn, Alison, Hu, Xin, Law, Brian K, Lu, Jianrong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093107/
https://ncbi.nlm.nih.gov/pubmed/20562920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.234
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