GATA2 regulates GATA1 expression through LSD1-mediated histone modification

The dynamic and reversed expression of GATA1 and GATA2 are essential for proper erythroid differentiation. Our previous work demonstrates that LSD1, a histone H3K4 demethylase, represses GATA2 expression at late stage of erythroid differentiation. K562 and MEL cells were used and cultured in Roswell...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Guo, Yidi, Fu, Xueqi, Huo, Bo, Wang, Yongsen, Sun, Jing, Meng, Lingyuan, Hao, Tian, Zhao, Zhizhuang Joe, Hu, Xin
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891438/
https://ncbi.nlm.nih.gov/pubmed/27347333
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