Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice

Pak1 plays an important role in various cellular processes, including cell motility, polarity, survival and proliferation. To date, its role in atherogenesis has not been explored. Here we report the effect of Pak1 on atherogenesis using atherosclerosis-prone apolipoprotein E-deficient (ApoE(−/−)) m...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Singh, Nikhlesh K., Kotla, Sivareddy, Dyukova, Elena, Traylor Jr., James G., Orr, A. Wayne, Chernoff, Jonathan, Marion, Tony N., Rao, Gadiparthi N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480433/
https://ncbi.nlm.nih.gov/pubmed/26104863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8450
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