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ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation

In understanding the mechanisms of cholesterol in the pathogenesis of atherosclerosis, previous studies from other laboratories have demonstrated that cholesterol crystals (CC) induce scavenger receptor CD36 expression and NLRP3-mediated inflammasome formation. In elucidating the mechanisms by which...

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Pubblicato in:Redox Biol
Autori principali: Kotla, Sivareddy, Singh, Nikhlesh K., Rao, Gadiparthi N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5200884/
https://ncbi.nlm.nih.gov/pubmed/28040583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.005
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