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The Transcription Factor CREB Enhances Interleukin-17A Production and Inflammation in a Mouse Model of Atherosclerosis

It has been demonstrated that 15-lipoxygenase (15-LO) plays a role in atherogenesis, but the underlying mechanisms were unclear. Therefore, the purpose of the present study is to explore the mechanisms of 15-LO role in atherogenesis. 15(S)-hydroxyeicosatetraenoic acid [15(S)-HETE], the major 15-LO-d...

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Bibliografiske detaljer
Main Authors: Kotla, Sivareddy, Singh, Nikhlesh K., Heckle, Mark R., Tigyi, Gabor J., Rao, Gadiparthi N.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931132/
https://ncbi.nlm.nih.gov/pubmed/24045154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004214
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