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Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors
The cell of origin of the five subtypes (I-V) of germ cell tumors (GCTs) are assumed to be germ cells from different maturation stages. This is (potentially) reflected in their methylation status as fetal maturing primordial germ cells are globally demethylated during migration from the yolk sac to...
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Publicado en: | PLoS One |
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Autores principales: | , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479500/ https://ncbi.nlm.nih.gov/pubmed/25859847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122146 |
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