טוען...
Negative cooperativity across β(1)-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation
At the β(1)-adrenoceptor, CGP 12177 potently antagonizes agonist responses at the primary high-affinity catecholamine conformation while also exerting agonist effects of its own through a secondary low-affinity conformation. A recent mutagenesis study identified transmembrane region (TM)4 of the β(1...
שמור ב:
| הוצא לאור ב: | FASEB J |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Federation of American Societies for Experimental Biology
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478806/ https://ncbi.nlm.nih.gov/pubmed/25837585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-265199 |
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