Activated Kupffer cells inhibit insulin sensitivity in obese mice

Obesity promotes insulin resistance associated with liver inflammation, elevated glucose production, and type 2 diabetes. Although insulin resistance is attenuated in genetic mouse models that suppress systemic inflammation, it is not clear whether local resident macrophages in liver, denoted Kupffe...

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Vydáno v:FASEB J
Hlavní autoři: Tencerova, Michaela, Aouadi, Myriam, Vangala, Pranitha, Nicoloro, Sarah M., Yawe, Joseph C., Cohen, Jessica L., Shen, Yuefei, Garcia-Menendez, Lorena, Pedersen, David J., Gallagher-Dorval, Karen, Perugini, Richard A., Gupta, Olga T., Czech, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2015
Témata:
Research Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478794/
https://ncbi.nlm.nih.gov/pubmed/25805830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-270496
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