Chromatin-Mediated Reversible Silencing of Sense-Antisense Gene Pairs in Embryonic Stem Cells Is Consolidated upon Differentiation

Genome-wide gene expression studies have indicated that the eukaryotic genome contains many gene pairs showing overlapping sense and antisense transcription. Regulation of these coding and/or noncoding gene pairs involves intricate regulatory mechanisms. In the present study, we utilized an enhanced...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Loos, Friedemann, Loda, Agnese, van Wijk, Louise, Grootegoed, J. Anton, Gribnau, Joost
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475928/
https://ncbi.nlm.nih.gov/pubmed/25963662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00029-15
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