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Silencing of proviruses in embryonic cells: efficiency, stability and chromatin modifications
Embryonic stem cells repress retroviral infection through transcriptional silencing of proviral DNAs. We characterized two distinct mechanisms of silencing in embryonic mouse cells infected by Moloney murine leukaemia virus (MLV): a highly efficient one targeting the proline transfer RNA primer-bind...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537137/ https://ncbi.nlm.nih.gov/pubmed/23154467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.182 |
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